Classic polyarteritis nodosa in childhood

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pANCA Positive Classic Polyarteritis Nodosa

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[Childhood cutaneous polyarteritis nodosa].

Cutaneous polyarteritis nodosa is an infrequent necrotizing vasculitis of small and medium-sized arteries, with a recurrent and chronic course, that can be associated with fever, arthralgia, myalgia and neuropathy without visceral involvement. We report a cutaneous polyarteritis nodosa case.

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Childhood polyarteritis nodosa: a clinical diagnosis.

A six-year old boy presented with dry gangrene of toes and fingers with hypertension with no other systemic abnormalities. He had persistently high inflammatory parameters, was diagnosed as childhood classic polyarteritis nodosa and showed improvement with immunosuppressants along with antihypertensives. Toe gangrene required amputation in view of superadded infection.

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Polyarteritis Nodosa

POLYARTERITIs NODosA, as its niame implies, is ain inflammatory lesion involving the -whole three coats of the arterial system in a noclal manner. The causation of this is unknown, but its peculiar affinity for wi(despread involvement of the smaller arteries results in a multiplicity of clinical signs and symptoms, and leads to confusion and difficulty in diagnosis. The more severely affected o...

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Polyarteritis Nodosa

Polyarteritis nodosa (PAN) is the systemic necrotizing vasculitis on small and median muscular vessels. Recent studies reveal that PAN consists of classical PAN and microscopic polyangitis (MPA). MPO-ANCA, which is one of anti-neutrophil cytoplasmic antibody (ANCA), is involved in the pathogenesis of MPA. In future, by the progress of research of ANCA, the definition or criteria of systemic vas...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology

سال: 2007

ISSN: 0019-5154

DOI: 10.4103/0019-5154.35096